Research guides

Reading a certificate of analysis

The fields that matter on a COA, and the ones that signal a document worth questioning.

Lot traceability

The lot code on the certificate must match the code printed on the vial. A certificate without a lot reference documents nothing in particular.

Who signed it

An independent laboratory, a release date and a named method carry more weight than an unattributed purity claim on a product page.

The supporting data

Look for the chromatogram and mass spectrum, not just a summary table. The raw trace is where peak shape, shoulders and baseline noise become visible.